Description
Director, Pharmacometrics, Clinical Pharmacology and Translational Medicine - Neurology Business Group
At Eisai, satisfying unmet medical needs and increasing the benefits healthcare provides to patients, their families, and caregivers is Eisai’s human health care (hhc) mission. We’re a growing pharmaceutical company that is breaking through in neurology and oncology, with a strong emphasis on research and development. Our history includes the development of many innovative medicines, notably the discovery of the world's most widely-used treatment for Alzheimer’s disease. As we continue to expand, we are seeking highly-motivated individuals who want to work in a fast-paced environment and make a difference. If this is your profile, we want to hear from you.
Job Summary
Eisai is searching for a creative, resourceful, integrative thinker who is driven to use cutting edge modeling approaches to advance the clinical and translational research in Neuroscience Business Group. This individual will provide scientific leadership to develop and execute impactful pharmacometric strategies in support of key decisions for programs across all phases of drug development. The complexity and scale of data being generated has grown significantly and requires strong scientific contributions to integrate different approaches in modeling, statistics and data science to bring value to the Eisai portfolio. This role requires diverse modeling experience in drug development within pharma/biotech, agility in being able to handle both hands-on modeling and strategic leadership for a dynamic project portfolio and a strong track-record of scientific and collaborative leadership in complex projects and initiatives.
Essential Functions
In-depth modeling skills, ability to translate complex problems into incisive models.
Develop and execute population PK, exposure response, mechanistic PK/PD models of neurodegenerative diseases, including physiologically-based pharmacokinetic (PBPK), quantitative system pharmacology (QSP) models, clinical trial simulations, literature meta-analysis, machine-learning/deep learning and other state of the art quantitative techniques.
Leverage pharmacometrics to make impactful contributions in drug development decision-making and regulatory submissions.
Represent Pharmacometrics and effectively communicate pharmacometric input to key management and decision boards.
Develop pharmacometrics strategies for Translational Medicine (in particular using continuous, longitudinal biomarkers) and various big, digital, historical data groups and initiatives.
Qualifications
PhD or PharmD in Pharmaceutical Sciences, Clinical Pharmacology, Applied Mathematics, Engineering or related area with strong background in the application of mathematical and statistical methods with 7+ years of experience
Proficiency in Non-linear mixed effects (NLME), mechanistic modeling approaches and using NONMEM, Monolix, R, Matlab or other modeling software.
Proficiency in written and verbal communication, interdisciplinary collaboration, and problem scoping and planning.
Experience and disease knowledge in neuroscience is preferable.
#LI-CC
Eisai Salary Transparency Language:
The base salary range for the Director, Pharmacometrics, Clinical Pharmacology and Translational Medicine - Neurology Business Group is from :213,000-279,600
Under current guidelines, this position is eligible to participate in : Eisai Inc. Annual Incentive Plan & Eisai Inc. Long Term Incentive Plan.
Final pay determinations will depend on various factors including but not limited to experience level, education, knowledge, and skills.
Employees are eligible to participate in Company employee benefit programs. For additional information on Company employee benefits programs, visit https://us.eisai.com/careers-at-eisai/benefits.
Certain other benefits may be available for this position, please discuss any questions with your recruiter.
Eisai is an equal opportunity employer and as such, is committed in policy and in practice to recruit, hire, train, and promote in all job qualifications without regard to race, color, religion, gender, age, national origin, citizenship status, marital status, sexual orientation, gender identity, disability or veteran status. Similarly, considering the need for reasonable accommodations, Eisai prohibits discrimination against persons because of disability, including disabled veterans.
Eisai Inc. participates in E-Verify. E-Verify is an Internet based system operated by the Department of Homeland Security in partnership with the Social Security Administration that allows participating employers to electronically verify the employment eligibility of all new hires in the United States. Please click on the following link for more information:
Right To Work
E-Verify Participation
